Opioid-Free anesthesia: a new way to manage pain after pancreatic surgery?

NCT ID NCT07364864

Not yet recruiting Symptom relief Sponsor: Jagiellonian University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares opioid-free anesthesia to standard opioid anesthesia in 200 adults undergoing pancreatic surgery. The goal is to see if avoiding opioids during surgery can still control pain well and reduce the need for painkillers afterward. Participants will have their pain levels and recovery quality measured for 48 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: opioid-free anesthesia (OFA) using non-opioid drugs
What this could lead to: If it works, this could offer a way to manage pain after major abdominal surgery without relying on opioids, reducing side effects and addiction risk.
What could go wrong: This is a small, early-stage study (200 people) that hasn't started recruiting yet. It may show that opioid-free anesthesia is less effective for some patients or has unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN MANAGEMENT

Contacts and locations

Locations

Department of Intensive Interdisciplinary Care, Collegium Medicum, Jagiellonian University

Krakow, Lesser Poland Voivodeship, 30688, Poland

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