Can eye tests track an inherited form of blindness?

NCT ID NCT07729982

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This study follows people with a genetic condition called OPA1-associated optic atrophy, which causes gradual vision loss. Researchers will use a battery of eye exams—including vision charts, contrast sensitivity, and retinal imaging—to see how the disease changes over time. The goal is to find reliable markers of disease severity and progression that could be used in future trials of potential treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could identify reliable ways to measure disease progression, paving the way for future treatment trials for this inherited cause of vision loss.
What could go wrong
This is an observational study, not a treatment trial, so it offers no direct benefit to participants. The findings may not translate into effective therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OPA1 GENE MUTATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Ophthalmology, LMU University Hospital, LMU Medizin, Ludwig-Maximilians-Universität München

    RECRUITING

    Munich, Bavaria, 80336, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.