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New study tracks emergency bleeding reversal drug in Real-World use

NCT ID NCT05454787

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This study monitors the safety and effectiveness of Ondexxya, a drug used to reverse the effects of certain blood thinners (apixaban, rivaroxaban, or edoxaban) during life-threatening or unstoppable bleeding. Researchers will track side effects and how well the drug works in 300 patients under real-world conditions. The goal is to better understand the drug's risks and benefits in emergency situations.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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    Phone: •••-•••-•••• Email: •••••@•••••

Locations

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    Aichi, Japan

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    Aichi, Japan

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    Aichi, Japan

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    Akita, Japan

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    Aomori, Japan

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    Chiba, Japan

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    Chiba, Japan

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    Chiba, Japan

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    Ehime, Japan

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    Ehime, Japan

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    Fukui, Japan

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    Fukui, Japan

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    Fukuoka, Japan

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    Fukuoka, Japan

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    Fukushima, Japan

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    Gifu, Japan

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    Gifu, Japan

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    Gunma, Japan

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    Gunma, Japan

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    Gunma, Japan

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    Hiroshima, Japan

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    Hokkaido, Japan

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    Hokkaido, Japan

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    Hyōgo, Japan

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    Hyōgo, Japan

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    Ibaraki, Japan

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    Ishikawa, Japan

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    Kagawa, Japan

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    Kagoshima, Japan

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    Kanagawa, Japan

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    Kanagawa, Japan

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    Kochi, Japan

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    Kumamoto, Japan

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    Kumamoto, Japan

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    Kyoto, Japan

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    Kyoto, Japan

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    Mie, Japan

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    Mie, Japan

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    Miyagi, Japan

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    Miyazaki, Japan

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    Nagano, Japan

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    Nagano, Japan

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    Nagasaki, Japan

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    Nagasaki, Japan

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    Nara, Japan

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    Niigata, Japan

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    Niigata, Japan

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    Numakunai, Japan

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    Okayama, Japan

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    Okinawa, Japan

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    Osaka, Japan

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    Osaka, Japan

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    Saga, Japan

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    Saitama, Japan

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    Shiga, Japan

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    Shiga, Japan

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    Shimane, Japan

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    Shizuoka, Japan

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    Tochigi, Japan

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    Tochigi, Japan

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    Tokushima, Japan

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    Tokyo, Japan

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    Tokyo, Japan

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    Tottori, Japan

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    Toyama, Japan

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    Wakayama, Japan

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    Wakayama, Japan

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    Yamagata, Japan

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    Yamagata, Japan

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    Yamaguchi, Japan

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    Yamaguchi, Japan

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    Yamanashi, Japan

Conditions

Explore the condition pages connected to this study.

FACTOR XA INHIBITOR LIFE THREATENING BLEEDING LIFE THREATENING BLEEDING