Stomach cancer surgery may get simpler: omentum preservation under study
NCT ID NCT05180864
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares two surgical approaches for stomach cancer: removing the entire omentum (a fatty layer in the abdomen) versus preserving it. The omentum helps fight infections and prevent bowel blockages. Researchers want to see if keeping it leads to fewer complications without affecting survival. About 654 adults with resectable stomach cancer will be randomly assigned to one of the two procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gastrectomy (surgery to remove part or all of the stomach)
- What this could lead to
- If successful, this could show that preserving the omentum during stomach cancer surgery is just as effective as removing it, while reducing complications like infections and bowel blockages.
- What could go wrong
- This is a non-inferiority trial, meaning it aims to prove that preserving the omentum is not worse than removing it. However, it is still recruiting and results are not yet available, so there is no guarantee of benefit or safety.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Amsterdam UMC
RECRUITINGAmsterdam, North Holland, 1081 HV, Netherlands
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Antoni van Leeuwenhoek
NOT_YET_RECRUITINGAmsterdam, Netherlands
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Azienda Ospedaliera Universitaria
NOT_YET_RECRUITINGSiena, Italy
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Catharina Ziekenhuis
RECRUITINGEindhoven, Netherlands
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Elisabeth Tweesteden ziekenhuis
NOT_YET_RECRUITINGTilburg, Netherlands
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Erasmus Medisch Centrum
NOT_YET_RECRUITINGRotterdam, Netherlands
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Gelre ziekenhuis
NOT_YET_RECRUITINGApeldoorn, Netherlands
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Leids Universitair Medisch Centrum
NOT_YET_RECRUITINGLeiden, Netherlands
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Medisch Centrum Leeuwarden
NOT_YET_RECRUITINGLeeuwarden, Netherlands
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Oxford University Hospitals
NOT_YET_RECRUITINGOxford, United Kingdom
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Rijnstate ziekenhuis
NOT_YET_RECRUITINGArnhem, Netherlands
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Universitair Medisch Centrum Utrecht
NOT_YET_RECRUITINGUtrecht, Netherlands
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Universitait Medisch Centrum Groningen
NOT_YET_RECRUITINGGroningen, Netherlands
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University Medical Center of the Johannes Gutenberg University
NOT_YET_RECRUITINGMainz, Germany
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Ziekenhuis Groep Twente
NOT_YET_RECRUITINGAlmelo, Netherlands
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Zuyderland ziekenhuis
NOT_YET_RECRUITINGHeerlen, Netherlands
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