Stomach cancer surgery may get simpler: omentum preservation under study

NCT ID NCT05180864

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two surgical approaches for stomach cancer: removing the entire omentum (a fatty layer in the abdomen) versus preserving it. The omentum helps fight infections and prevent bowel blockages. Researchers want to see if keeping it leads to fewer complications without affecting survival. About 654 adults with resectable stomach cancer will be randomly assigned to one of the two procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gastrectomy (surgery to remove part or all of the stomach)

What this could lead to

If successful, this could show that preserving the omentum during stomach cancer surgery is just as effective as removing it, while reducing complications like infections and bowel blockages.

What could go wrong

This is a non-inferiority trial, meaning it aims to prove that preserving the omentum is not worse than removing it. However, it is still recruiting and results are not yet available, so there is no guarantee of benefit or safety.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam UMC

    RECRUITING

    Amsterdam, North Holland, 1081 HV, Netherlands

    Contact

  • Antoni van Leeuwenhoek

    NOT_YET_RECRUITING

    Amsterdam, Netherlands

  • Azienda Ospedaliera Universitaria

    NOT_YET_RECRUITING

    Siena, Italy

  • Catharina Ziekenhuis

    RECRUITING

    Eindhoven, Netherlands

  • Elisabeth Tweesteden ziekenhuis

    NOT_YET_RECRUITING

    Tilburg, Netherlands

  • Erasmus Medisch Centrum

    NOT_YET_RECRUITING

    Rotterdam, Netherlands

  • Gelre ziekenhuis

    NOT_YET_RECRUITING

    Apeldoorn, Netherlands

  • Leids Universitair Medisch Centrum

    NOT_YET_RECRUITING

    Leiden, Netherlands

  • Medisch Centrum Leeuwarden

    NOT_YET_RECRUITING

    Leeuwarden, Netherlands

  • Oxford University Hospitals

    NOT_YET_RECRUITING

    Oxford, United Kingdom

  • Rijnstate ziekenhuis

    NOT_YET_RECRUITING

    Arnhem, Netherlands

  • Universitair Medisch Centrum Utrecht

    NOT_YET_RECRUITING

    Utrecht, Netherlands

  • Universitait Medisch Centrum Groningen

    NOT_YET_RECRUITING

    Groningen, Netherlands

  • University Medical Center of the Johannes Gutenberg University

    NOT_YET_RECRUITING

    Mainz, Germany

  • Ziekenhuis Groep Twente

    NOT_YET_RECRUITING

    Almelo, Netherlands

  • Zuyderland ziekenhuis

    NOT_YET_RECRUITING

    Heerlen, Netherlands