Can a heart drug make Omega-3 supplements work better?

NCT ID NCT07304921

Completed Knowledge-focused Sponsor: Riga Stradins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This completed Phase 1 trial in 48 healthy adults tested whether taking meldonium (a drug) together with omega-3 supplements (EPA and DHA) increases omega-3 levels in the blood more than omega-3 alone. Participants were split into three groups and took different combinations over 8 weeks. The study measured blood levels of omega-3s and related fat metabolites, but did not treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Meldonium and omega-3 (EPA/DHA) supplements
What this could lead to: If it works, this could point toward a way to increase omega-3 levels in the blood more efficiently, which may help in conditions linked to low omega-3.
What could go wrong: This is a very early, small study in healthy volunteers, not patients. It only measures blood levels, not health outcomes. Results may not apply to people with diseases.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIPID METABOLISM OMEGA-3 POLYUNSATURATED FATTY ACIDS SUPPLEMENTATION

Contacts and locations

Locations

Riga Stradins university

Riga, Latvia

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