Fish oil meets TB drugs: can Omega-3 help clear infection faster?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adults aged 18-45 years * laboratory confirmed Pulmonary TB defined as a hard copy of a sputum result detected by WHO recommended assay or mycobacteria culture. * Women of childbearing potential with a negative pregnancy test on enrollment * All participant irrespective of HIV status who consent to have a HIV test during enrollment. Exclusion Criteria: * Comorbid condition with treatment of NSAIDS is indicated * Institutionalized or incarcerated individuals * Those on Multiple drug resistance treatment for more than 4 days within the past 6 months or within 1 month to prior to TB treatment initiation * Pregnant or breastfeeding women or women who become pregnant in the first 4 weeks of the trial will be withdrawn * show lab safety values: AST or ALT \> x3 upper limit of normal (ULN) or Total bilirubin \> 2x the ULN, Neutrophils ≤ 700/mm³, Platelets \< 50,000/mm³, Haemoglobin \< 8 g/dL, Serum creatinine \> 2× ULN. * Are receiving or planning treatment with any of the following in the 3 months before or during the trial: Anticoagulants Immune-modulating therapy (e.g., cancer treatment, oral/inhaled corticosteroids) Antacids or proton pump inhibitors (PPIs) * Have a known allergy or sensitivity to fish or fish oil. * Have a recent history (within 2 years) or current clinical evidence of: Peptic ulcer disease or GI bleeding Coagulopathy or bleeding disorders Kidney or liver disease requiring hospitalisation Cardiovascular disease or significant risk factors for it -Are HIV-positive and meet any of the following: CD4 count \< 100 cells/mm³ Viral load \> 400 copies/mL (if on ART) Not yet on ART but are expected to initiate treatment during the 8-week intervention phase * Report high-risk alcohol use (average \>4 units/day or binge drinking patterns) * Have any other medical condition or situation that, in the investigator's opinion, may interfere with protocol adherence or data interpretation. * Plan to relocate from the study area within the next 3 months. * Are currently using omega-3 or omega-6 supplements and are unwilling to stop for the duration of the study.