New opioid aims to quiet cough during anesthesia

NCT ID NCT07660380

Recruiting now Symptom relief Sponsor: Shiyou Wei Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This trial tests whether oliceridine, a newer opioid, causes less coughing than the standard drug sufentanil when given at the start of general anesthesia. Coughing during this phase can be dangerous, especially for patients with high pressure in the head or eyes. The study involves adults scheduled for elective surgery and will measure cough frequency, severity, and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Oliceridine
What this could lead to: If oliceridine causes less coughing than sufentanil during anesthesia induction, it could become a safer option for patients, especially those at risk of complications from coughing.
What could go wrong: This is a small, single-center trial, so results may not apply to all patients. Oliceridine may not reduce cough as hoped, or could have other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANESTHESIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Cough

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA COUGH

Contacts and locations

Locations

Tianmen First People's Hospital
RECRUITING

Tianmen, Hubei, 431700, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.