New opioid aims to quiet cough during anesthesia

NCT ID NCT07660380

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether oliceridine, a newer opioid, causes less coughing than the standard drug sufentanil when given at the start of general anesthesia. Coughing during this phase can be dangerous, especially for patients with high pressure in the head or eyes. The study involves adults scheduled for elective surgery and will measure cough frequency, severity, and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Oliceridine

What this could lead to

If oliceridine causes less coughing than sufentanil during anesthesia induction, it could become a safer option for patients, especially those at risk of complications from coughing.

What could go wrong

This is a small, single-center trial, so results may not apply to all patients. Oliceridine may not reduce cough as hoped, or could have other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cough

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianmen First People's Hospital

    Tianmen, Hubei, 431700, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••