New opioid aims to ease pain without slowing digestion

NCT ID NCT07307495

First seen Jan 04, 2026 · Last updated May 12, 2026 · Updated 18 times

Summary

This study tests a new pain medicine, oliceridine fumarate, in 428 adults having lumbar spine surgery. The goal is to see if it controls pain as well as standard opioids but helps the gut recover faster (eating solid food and passing gas). Participants will be randomly assigned to receive oliceridine or a placebo after surgery, and their recovery will be tracked for 48 hours.

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