New study pinpoints oliceridine dose to keep blood pressure steady during intubation

NCT ID NCT07154979

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested different doses of oliceridine, a painkiller, to find the amount that best prevents sudden rises in blood pressure and heart rate when a breathing tube is placed during anesthesia. Researchers enrolled 58 adults having elective surgery and adjusted doses based on age. The goal was to identify the effective dose for safer anesthesia induction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oliceridine (TRV130)

What this could lead to

If successful, this could help doctors choose the safest dose of oliceridine to prevent dangerous blood pressure spikes during anesthesia, especially for older patients.

What could go wrong

This is a small, completed dose-finding study, not a large trial testing long-term outcomes. The results may not apply to all patients or settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tianmen First People's Hospital

    Tianmen, Hubei, 431700, China