New pill targets Cancer's weak spot: a hopeful trial for Tough-to-Treat tumors

NCT ID NCT03375307

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a pill called olaparib can help control advanced bladder and other urinary cancers that have specific DNA repair defects and have stopped responding to standard treatments like chemotherapy. The drug works by blocking a protein that helps cancer cells fix their DNA, which may cause the tumor cells to die. The main goal is to see if the treatment shrinks tumors in patients whose cancers have spread and are no longer controlled by other therapies.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Huntsman Cancer Institute/University of Utah
SUSPENDED

Salt Lake City, Utah, 84112, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone
ACTIVE_NOT_RECRUITING

New York, New York, 10016, United States
Los Angeles General Medical Center
ACTIVE_NOT_RECRUITING

Los Angeles, California, 90033, United States
NCI - Center for Cancer Research
RECRUITING

Bethesda, Maryland, 20892, United States

Contact

Contact Phone: •••-•••-••••
NYP/Weill Cornell Medical Center
SUSPENDED

New York, New York, 10065, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center
SUSPENDED

Orange, California, 92868, United States
UC San Diego Health System - Encinitas
SUSPENDED

Encinitas, California, 92024, United States
UC San Diego Medical Center - Hillcrest
RECRUITING

San Diego, California, 92103, United States

Contact

Contact Email: •••••@•••••
UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UCHealth University of Colorado Hospital
RECRUITING

Aurora, Colorado, 80045, United States

Contact Phone: •••-•••-••••

Contact
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
SUSPENDED

Irvine, California, 92612, United States
USC / Norris Comprehensive Cancer Center
ACTIVE_NOT_RECRUITING

Los Angeles, California, 90033, United States
USC Norris Oncology/Hematology-Newport Beach
ACTIVE_NOT_RECRUITING

Newport Beach, California, 92663, United States
University of California Davis Comprehensive Cancer Center
SUSPENDED

Sacramento, California, 95817, United States
University of Kentucky/Markey Cancer Center
ACTIVE_NOT_RECRUITING

Lexington, Kentucky, 40536, United States
University of Oklahoma Health Sciences Center
ACTIVE_NOT_RECRUITING

Oklahoma City, Oklahoma, 73104, United States
University of Texas Medical Branch
SUSPENDED

Galveston, Texas, 77555-0565, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED BLADDER CARCINOMA ADVANCED GENITOURINARY SYSTEM CARCINOMA METASTATIC BLADDER CARCINOMA METASTATIC GENITOURINARY SYSTEM CARCINOMA STAGE III BLADDER CANCER AJCC V8 STAGE IV BLADDER CANCER AJCC V8