Olaparib shows promise for Early-Stage prostate cancer recurrence

NCT ID NCT03047135

First seen May 13, 2026 ยท Last updated May 13, 2026

Summary

This study tests the drug olaparib in 51 men whose prostate cancer has returned after surgery and is at high risk of spreading. Olaparib works by blocking a repair process in cancer cells, and early studies suggest it may be more effective when given earlier in the disease. The main goal is to see if olaparib can lower PSA levels by at least 50%.

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Contacts and locations

Locations

  • Allegheny Cancer Center

    Pittsburgh, Pennsylvania, 15212, United States

  • Johns Hopkins Hospital

    Baltimore, Maryland, 21231, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.