Hidden brain fog in obesity breathing disorder may undermine recovery
NCT ID NCT07147153
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This study looks at how sleep quality, thinking abilities, and physical function are related in people with obesity hypoventilation syndrome (OHS), a severe breathing condition linked to obesity. Researchers will compare 18 people with OHS to 18 people with simple obesity using walking tests, cognitive assessments, and sleep questionnaires. The goal is to uncover whether undetected thinking problems affect how well patients can participate in rehabilitation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If links are found, it may help design better rehab programs for people with OHS by addressing thinking problems early.
- What could go wrong
- This is a small observational study with only 36 people, so findings may not apply to everyone. It measures associations, not causes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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36 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Individuals with Obesity Hypoventilation Syndrome who applied to the Department of Pulmonary Diseases at Istanbul University Istanbul Faculty of Medicine, met the inclusion criteria for the study, and were diagnosed through polysomnographic evaluation by a Pulmonary Disease specialist.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 65 years * Diagnosed with OHS by a pulmonologist * For individuals with simple obesity: BMI between 30 and 40 kg/m², Apnea-Hypopnea Index (AHI) \< 5 on polysomnography, or STOP-Bang score \< 3 * Ability to communicate in written and spoken Turkish Exclusion Criteria: * Presence of any additional severe respiratory disease * Presence of orthopedic, neurological, cardiovascular, or respiratory conditions preventing exercise testing * For individuals with simple obesity: presence of OSAS risk factors such as severe snoring or witnessed apnea * Presence of any psychological or psychiatric disorder that could affect cognitive functions
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul University, Istanbul Faculty of Medicine
Istanbul, Turkey (Türkiye)
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