Could a blood pressure pill curb heavy drinking in HIV patients?
NCT ID NCT06004830
First seen Oct 31, 2025 · Last updated Jun 19, 2026 · Updated 33 times
Summary
This small pilot study tested whether spironolactone, a medication usually used for heart conditions, could help people with HIV reduce their alcohol use. Twenty-one participants received the drug along with support from a pharmacist and psychiatrist. The study focused on whether this approach was practical and safe, and whether it might lead to less drinking.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atlanta VA Medical Center
Decatur, Georgia, 30033, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
spironolactone
What this could lead to
If this approach works, it could offer a new way to help people with HIV reduce their drinking, potentially improving their overall health.
What could go wrong
This is a very small pilot study with only 21 participants and no comparison group. The results may not apply to a larger population, and spironolactone's effectiveness for alcohol use disorder is not yet proven.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.