Eye blood flow camera could spot glaucoma before vision fades

NCT ID NCT05726058

Recruiting now Diagnosis Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether a special camera that measures blood flow in the retina can help tell the difference between healthy eyes and those with early glaucoma. Researchers will compare images from the XyCAM device with standard eye exams in 150 adults, including healthy volunteers and people with or at risk for glaucoma. Participants also inhale pure oxygen during imaging to see how blood flow changes. The goal is to see if this non-invasive tool can improve early detection of glaucoma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: XyCAM RI and XyCAM FC (retinal blood flow imaging device)
What this could lead to: If successful, this could provide a new, non-invasive way to detect glaucoma earlier, potentially preventing vision loss.
What could go wrong: This is an early-stage diagnostic study, not a treatment trial. The device may not prove accurate enough for widespread use, and results may not change current care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

eye disorder glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLAUCOMA

Contacts and locations

Locations

University of Maryland Eye Associates at Redwood
RECRUITING

Baltimore, Maryland, 21201, United States

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