Gene therapy slows vision loss in stargardt disease trial
NCT ID NCT05956626
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests a new gene therapy called OCU410ST for people with Stargardt disease, an inherited eye condition that causes vision loss. Early results show the treatment slowed damage to the retina by nearly half and improved or stabilized eyesight in all treated patients. The trial now enrolls 51 participants aged 5 and older to confirm these benefits and check safety.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Research, LLC
Pompano Beach, Florida, 33064, United States
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Associated Retina Consultants
Phoenix, Arizona, 85020, United States
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Bascom Palmer Eye Institute
Miami, Florida, 33136, United States
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Duke Eye Center
Durham, North Carolina, 27710, United States
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Erie Retina Research, LLC
Erie, Pennsylvania, 16505, United States
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Mississippi Retina Associates
Jackson, Mississippi, 39202, United States
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Retina Consultants of Texas
Bellaire, Texas, 77401, United States
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Retina Foundation of the Southwest
Dallas, Texas, 75231, United States
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Retina Partners Midwest, P.C.
Carmel, Indiana, 46032, United States
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Retinal Consultants Medical Group
Sacramento, California, 95825, United States
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The Retina Institute
St Louis, Missouri, 63128, United States
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Valley Retina Institute
McAllen, Texas, 78503, United States
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Vitreo Retinal Associates, P.A.
Gainesville, Florida, 32607, United States