New eye on pancreatic cancer: Ultra-High resolution OCT could catch tumors at micrometer scale

NCT ID NCT03711890

Recruiting now Diagnosis Sponsor: Ohio State University Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a high-powered imaging technique called ultra-high resolution optical coherence tomography (OCT) can detect tiny, early-stage pancreatic cancers in tissue samples removed during surgery. Researchers will compare OCT images with standard lab analysis and a blood test that looks for cancer-related particles. The goal is to see if OCT can identify cancers that are too small to spot with current methods.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Optical Coherence Tomography (OCT) imaging
What this could lead to: If successful, this imaging technique could help doctors spot pancreatic cancer at a much earlier, more treatable stage.
What could go wrong: This is a small pilot study using tissue already removed during surgery, so it may not translate to real-time detection in living patients.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma pancreatic adenocarcinoma Pancreatic Intraductal Neoplasms pancreatic intraductal papillary-mucinous neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CARCINOMA PANCREATIC INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM, PANCREATOBILIARY-TYPE

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210, United States

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