Pregnancy drug study checks immune cells in newborns

NCT ID NCT04998812

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 26 times

Summary

This study checked how much of the multiple sclerosis drug ocrelizumab passes from mother to baby during pregnancy. Researchers measured B cell levels in 70 infants whose mothers took the drug before or early in pregnancy. The goal was to understand the drug's effect on the baby's immune system.

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Contacts and locations

Locations

  • Hopital Pierre Wertheimer - Hopital Neurologique

    Bron, 69003, France

  • Hosp. Clinico San Carlos

    Madrid, 28040, Spain

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Hôpital de la Pitié Salpétrière

    Paris, 75013, France

  • Inselspital Bern

    Bern, 3010, Switzerland

  • MultipEL Studies - Institut für klinische Studien

    Hamburg, 22179, Germany

  • St. Josef Hospital GmbH

    Bochum, 44791, Germany

  • The Ken and Ruth Davee department of Neurology

    Chicago, Illinois, 60611-4296, United States

  • University Of Colorado

    Aurora, Colorado, 80045, United States

  • University of California San Francisco

    San Francisco, California, 94158, United States

  • Universitätsspital Basel

    Basel, 4031, Switzerland

Conditions

Explore the condition pages connected to this study.