Could schizophrenia be an autoimmune brain disease? new trial aims to find out

NCT ID NCT03971487

First seen Apr 13, 2026 · Last updated May 13, 2026 · Updated 9 times

Summary

This study explores whether some cases of schizophrenia or schizoaffective disorder are actually caused by the immune system attacking the brain. Researchers are giving an immune-suppressing drug called ocrelizumab to 40 adults aged 18-35 who developed psychosis after age 15. The goal is to see if reducing these auto-antibodies improves symptoms like hallucinations and thinking problems.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Houston Methodist Research Institute

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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