New heart device aims to patch holes without surgery

NCT ID NCT05329350

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called the Occlutech mVSD Occluder to close a type of hole in the heart (muscular ventricular septal defect) without open surgery. The device is inserted through a blood vessel in the leg and guided to the heart. Researchers will follow 50 patients for one year to see if the device safely closes the hole and reduces blood flow problems. The goal is to offer a less invasive treatment option for people with this heart condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Occlutech muscular ventricular septal defect (mVSD) occluder (a self-expanding mesh device implanted via catheter to close a hole in the heart)

What this could lead to

If successful, this device could offer a less invasive, non-surgical option to close muscular ventricular septal defects, potentially reducing recovery time and surgical risks.

What could go wrong

This is a small, early-stage follow-up study with only 50 participants. The device may cause serious complications like stroke, heart block, or device movement. Long-term benefits and risks are not yet fully known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital heart disease ventricular septal defect

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Health Ireland

    NOT_YET_RECRUITING

    Dublin, N512, Ireland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dicle Üniversitesi Tıp Fakültesi Hastanesi

    NOT_YET_RECRUITING

    Diyarbakır, Sur, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Eskişehir Osmangazi Üniversite Hastanesi

    NOT_YET_RECRUITING

    Eskişehir, Odunpazarı, 26040, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gaziantep Unıversıty Hospital

    RECRUITING

    Gaziantep, Şehitkamil, 27310, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • İzmir Şehir Hastanesi

    NOT_YET_RECRUITING

    Izmir, Bayraklı, 35540, Turkey (Türkiye)

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact