New heart device aims to patch holes without surgery

NCT ID NCT05329350

First seen Jun 26, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study is testing a device called the Occlutech mVSD Occluder to close a type of hole in the heart (muscular ventricular septal defect) without open surgery. The device is inserted through a blood vessel in the leg and guided to the heart. Researchers will follow 50 patients for one year to see if the device safely closes the hole and reduces blood flow problems. The goal is to offer a less invasive treatment option for people with this heart condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Occlutech muscular ventricular septal defect (mVSD) occluder (a self-expanding mesh device implanted via catheter to close a hole in the heart)
What this could lead to
If successful, this device could offer a less invasive, non-surgical option to close muscular ventricular septal defects, potentially reducing recovery time and surgical risks.
What could go wrong
This is a small, early-stage follow-up study with only 50 participants. The device may cause serious complications like stroke, heart block, or device movement. Long-term benefits and risks are not yet fully known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Health Ireland

    NOT_YET_RECRUITING

    Dublin, N512, Ireland

  • Dicle Üniversitesi Tıp Fakültesi Hastanesi

    NOT_YET_RECRUITING

    Diyarbakır, Sur, Turkey (Türkiye)

  • Eskişehir Osmangazi Üniversite Hastanesi

    NOT_YET_RECRUITING

    Eskişehir, Odunpazarı, 26040, Turkey (Türkiye)

  • Gaziantep Unıversıty Hospital

    RECRUITING

    Gaziantep, Şehitkamil, 27310, Turkey (Türkiye)

  • Royal Brompton Hospital

    NOT_YET_RECRUITING

    London, England, SW3 6NP, United Kingdom

  • İzmir Şehir Hastanesi

    NOT_YET_RECRUITING

    Izmir, Bayraklı, 35540, Turkey (Türkiye)

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