Inside the body: new study scans how Weight-Loss drugs hit brain and pancreas receptors
NCT ID NCT05202353
First seen Oct 01, 2025 · Last updated May 15, 2026 · Updated 29 times
Summary
This study looks at how two weight-loss drugs, BI 456906 and semaglutide, attach to receptors in the liver and pancreas. About 30 adults with obesity will get either drug for 17 weeks. Before and after treatment, doctors use PET and MRI scans to see how much the drugs occupy these receptors. The goal is to understand how these drugs work in the body, not to test if they help with weight loss.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBESITY are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Amsterdam UMC, location VUMC
RECRUITINGAmsterdam, 1105 AZ, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.