New obesity drug MBX 4291 enters first human safety trial

NCT ID NCT07142707

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 30 times

Summary

This early-stage study tests a new drug called MBX 4291 in 124 adults with obesity (BMI 30 to under 50). The main goal is to see if the drug is safe and how well people tolerate it. Participants receive either the drug or a placebo as an injection under the skin. The study is currently recruiting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBESITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MBX Biosciences Investigational Site

    RECRUITING

    Lexington, Kentucky, 40509, United States

  • MBX Biosciences Investigational Site

    RECRUITING

    Knoxville, Tennessee, 37920, United States

Conditions

Explore the condition pages connected to this study.