Why losing weight is so hard: brain reward signals may be broken
NCT ID NCT02241603
First seen May 14, 2026 · Last updated May 15, 2026 · Updated 1 time
Summary
This study looked at 37 obese adults to understand why their brains show less pleasure when tasting food. Researchers think insulin resistance in the brain may be the cause. They used brain scans to measure responses and checked if weight loss could fix the problem. The goal is to learn why weight loss is difficult and find new ways to treat obesity.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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St. Louis VA Medical Center John Cochran Division, St. Louis, MO
St Louis, Missouri, 63106, United States
Conditions
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