Experimental virus therapy for solid tumors shows early promise in terminated trial

NCT ID NCT06063317

First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This early-phase study tested a new treatment called onCARlytics (CF33-CD19), a virus designed to infect and kill cancer cells, given together with another drug (blinatumomab) in adults with advanced solid tumors that had not responded to prior therapies. The trial aimed to find the safest dose and check for side effects. It was terminated early, but the data collected helps researchers understand how this combination works.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SOLID TUMOR, ADULT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Emory Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Northwestern

    Chicago, Illinois, 60208, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14203, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15219, United States

Conditions

Explore the condition pages connected to this study.