Could a knee replacement leave patients malnourished?
NCT ID NCT07782502
First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time
Summary
This study investigates whether total knee replacement surgery can cause or worsen malnutrition in adults. Researchers will measure nutritional status through blood tests and physical performance tests before and after surgery in 60 patients. The goal is to understand if this type of surgery poses a hidden nutritional risk that has not been studied before.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Additional postoperative blood tests and physical performance tests (hand grip, calf circumference, walking, chair stand, Timed Up & Go)
- What this could lead to
- If this study shows that knee replacement surgery can trigger or worsen malnutrition, it could lead to routine nutritional screening and support for patients before and after surgery.
- What could go wrong
- This is a small exploratory study, so findings may not apply to all patients. It only measures nutritional status, not whether any intervention improves outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female patients aged ≥18 years at the time of surgery * Patients scheduled for total knee arthroplasty. * Patients enrolled in the preoperative Enhanced Recovery After Surgery (ERAS) pathway. * Patients affiliated with or covered by a social security system. * French-speaking patients who have provided written informed consent Exclusion Criteria: * Patients scheduled for revision total knee arthroplasty * Protected patients: adults under guardianship, curatorship, or other legal protection measures, or individuals deprived of liberty by judicial or administrative decision * Patients hospitalized without consent.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Clinique des Maussins
Paris, 75850, France
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