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Could a simple nutritional plan boost survival after liver procedure?

NCT ID NCT06814626

Recruiting now Disease control Sponsor: The Mediterranean Institute for Transplantation and Advanced Specialized Therapies Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial investigates whether a 12-week nutritional intervention, including a personalized diet and a supplement called Friliver, can improve six-month survival in people with liver cirrhosis who have muscle loss (sarcopenia) and fluid buildup (refractory ascites). Participants receive the intervention after a procedure called TIPS, which helps manage fluid buildup. The study compares survival rates between those who get the nutritional support and those who do not.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a dietary supplement called Friliver (amino acids and nutrients) plus a personalized diet
What this could lead to
If successful, this nutritional approach could improve survival and muscle health in people with advanced liver disease undergoing TIPS.
What could go wrong
This is a small, early-phase trial with only 72 participants, so results may not apply to all patients. The supplement may not be effective or could cause digestive side effects.

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Conditions

The condition(s) this trial relates to.

Ascites cirrhosis of liver Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER CIRRHOSIS REFRACTORY ASCITES IN PATIENTS WITH CIRRHOSIS SARCOPENIA IN LIVER CIRRHOSIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS ISMETT - Istituto Mediterraneo per i Trapianti e le Terapie ad Alta Specializzazione

    RECRUITING

    Palermo, 90127, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Clinic for Visceral Surgery and Medicine, Inselspital

    RECRUITING

    Bern, 3010, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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