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Supplements and talk therapy may ease Alcohol's toll on the liver

NCT ID NCT07603726

Disease control Sponsor: Medical Center TOPMED Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested whether a combination of nutraceutical supplements and psychological support could lower GGT, a liver enzyme, in 197 adults with alcohol use disorder. Participants received liver-supporting supplements and counseling to reduce drinking. The goal was to see if this dual approach could reduce alcohol-related liver stress.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nutraceutical supplements (hepatoprotective compounds)
What this could lead to
If successful, this combined approach could offer a practical way to reduce alcohol-related liver stress and support recovery in people with alcohol use disorder.
What could go wrong
This is a completed early-stage study with no phase designation, so results may not be definitive. The intervention is not a cure and relies on participants' adherence to both supplements and counseling.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

197 people

The number who actually took part.

Started

Jan 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Diagnosis of Alcohol Use Disorder * Elevated baseline gamma-glutamyl transferase (GGT) levels * Ability to provide informed consent Exclusion Criteria: * Severe liver disease (e.g., cirrhosis or hepatic failure) * Severe psychiatric disorders interfering with participation * Current participation in another clinical study * Incomplete clinical or laboratory data

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol use disorder (AUD)

Contacts and locations

Locations

  • Medical Center TOPMED

    Târgu Mureş, Mureș County, 540058, Romania

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