Experimental drug aims to halt liver failure in cirrhosis patients

NCT ID NCT07694297

Not yet recruiting Disease control Sponsor: Genfit Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests whether adding the drug NTZ to standard care can help people with liver cirrhosis who experience a sudden worsening (acute decompensation) or have developed acute-on-chronic liver failure. The trial enrolls adults with cirrhosis from any cause who have had a recent acute decline. Researchers are primarily checking if NTZ is safe and tolerable in this setting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
NTZ (nitazoxanide)
What this could lead to
If successful, this could offer a new treatment option to stabilize patients with acute liver decompensation or early liver failure, potentially reducing progression and improving survival.
What could go wrong
This is an early-phase trial with only 16 participants, so results may not apply broadly. NTZ may cause side effects or fail to show benefit over standard care alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute-On-Chronic Liver Failure cirrhosis of liver liver failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••