Why do period pills fail? new study probes Brain's role in menstrual pain

NCT ID NCT05900336

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 32 times

Summary

This study looked at 70 women with severe menstrual pain to understand why some don't get relief from NSAIDs like ibuprofen. Researchers measured pain sensitivity and brain processing to see if changes in the nervous system (central sensitization) play a role. The goal is to identify women at risk for chronic pain and improve treatments.

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Contacts and locations

Locations

  • McLean Hospital

    Belmont, Massachusetts, 02478, United States

Conditions

Explore the condition pages connected to this study.