New eye drops aim to tame uveitis without steroids

NCT ID NCT07285070

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests NOV05, a water-free tacrolimus eye drop, in 20 adults with active non-infectious anterior uveitis. Participants receive either a high or low dose for 6 weeks. The goal is to see if it safely controls inflammation and reduces the need for steroid eye drops.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tacrolimus eye drops

What this could lead to

If successful, this could provide a steroid-sparing option to control eye inflammation in uveitis patients.

What could go wrong

This is a small, early-phase proof-of-concept study with only 20 participants. The treatment may not prove effective or safe enough to advance.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-infectious anterior uveitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bascom Palmer Eye Institute

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts Eye Research and Surgery Institution

    RECRUITING

    Waltham, Massachusetts, 02451, United States

    Contact Phone: •••-•••-••••

  • Metropolitan Eye Research and Surgery Institute

    RECRUITING

    Palisades Park, New Jersey, 07650, United States

    Contact Phone: •••-•••-••••

  • Valley Retina Institute, P.A.

    RECRUITING

    McAllen, Texas, 78503, United States

    Contact Phone: •••-•••-••••

  • Virginia Eye Consultants

    RECRUITING

    Norfolk, Virginia, 23502, United States

    Contact Phone: •••-•••-••••