Immune cells take on stubborn stomach virus in transplant patients

NCT ID NCT04691622

First seen Jan 31, 2026 · Last updated May 12, 2026 · Updated 13 times

Summary

This early-stage study tests whether giving special immune cells (norovirus-specific T-cells) is safe for people with chronic norovirus infection who have weak immune systems due to stem cell or organ transplants or primary immune disorders. About 48 participants will receive the cells and be monitored for side effects like graft-versus-host disease. The goal is to see if this approach can help control the virus without causing serious harm.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's National Hospital

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • National Institutes of Health (NIH)

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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