New Non-Opioid drug could cut painkiller use after knee surgery
NCT ID NCT07357376
First seen Jan 22, 2026 · Last updated May 13, 2026 · Updated 11 times
Summary
This study tests whether a non-opioid pain medicine called suzetrigine can reduce the need for opioid painkillers after total knee replacement. About 210 adults having knee surgery will take either suzetrigine or a placebo for 14 days after their operation. Researchers will track how much opioid medicine they use, their pain levels, and how well they recover.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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