Radiation-Chemo combo may let rectal cancer patients skip surgery
NCT ID NCT03904043
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a short course of radiation followed by chemotherapy could eliminate the need for surgery in people with early-stage rectal cancer. 63 patients were enrolled, and the treatment aimed for a complete clinical response, meaning no tumor could be found on exams or scans. The approach builds on earlier promising results and offers a potential non-surgical option for eligible patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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University of Colorado
Aurora, Colorado, 80045, United States
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University of Vermont Medical Center
Burlington, Vermont, 05401, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States