MRI may replace surgery to spot shunt clogs in brain fluid disorder

NCT ID NCT07172841

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study will test whether MRI scans can detect a blocked shunt in adults with normal pressure hydrocephalus without needing surgery. Sixty participants will have their shunt temporarily set to 'off' for 5-7 days to mimic a blockage. Researchers will compare MRI images and blood tests before, during, and after this period to see if they can spot the obstruction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a non-invasive way to diagnose shunt blockages in hydrocephalus patients, reducing the need for exploratory surgery.
What could go wrong
This is a small, early-stage study (60 people) that only simulates a blockage for a few days. Real-world blockages may behave differently, and the method may not be accurate enough for clinical use.

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Conditions

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As listed by the trial registrant

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