Could a simple ultrasound replace liver biopsies for kids?

NCT ID NCT07202910

Recruiting now Diagnosis Sponsor: Sahlgrenska University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether special ultrasound scans can accurately detect liver damage in children without needing a needle biopsy. Researchers will compare these scans to standard biopsy results in 550 children with various liver conditions. If the scans prove reliable, they could offer a safer, painless way to monitor liver health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ultrasound imaging (shear wave elastography, shear wave dispersion, attenuation imaging)
What this could lead to: If successful, this could allow doctors to diagnose and monitor liver disease in children using a simple ultrasound instead of a needle biopsy.
What could go wrong: This is an early validation study, not a treatment trial. The imaging methods may not be accurate enough to replace biopsies in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Congenital Abnormalities cystic fibrosis-related liver disease Digestive System Diseases intestinal failure–associated liver disease liver disorder metabolic dysfunction-associated steatotic liver disease Obesity Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTIC FIBROSIS LIVER DISEASE HEPATIC DISORDERS INTESTINAL FAILURE-ASSOCIATED LIVER DISEASE MAFLD PEDIATRIC LIVER TRANSPLANTATION

Contacts and locations

Locations

Department of Radiology, Queen Silvias Children´s Hospital,Gothenburg Sweden
RECRUITING

Gothenburg, Västra Götaland County, 41650, Sweden

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