New immune therapy aims to save lives in severe pneumonia

NCT ID NCT07492875

First seen Apr 08, 2026 · Last updated Apr 29, 2026 · Updated 3 times

Summary

This study tests whether adding an experimental drug (nogapendekin alfa inbakicept) and special immune cells (iNKT cells) to standard care can lower the death rate in critically ill adults with severe pneumonia, often complicated by sepsis or lung failure. About 10 participants in the ICU will receive either the new treatment or a placebo, and researchers will track survival and recovery over 28 days. The goal is to see if this approach can help the body fight infection better.

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