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Shocking muscles back to health: new trial for ICU patients

NCT ID NCT07566702

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether neuromuscular electrical stimulation (NMES) can help preserve muscle mass in critically ill patients on ECMO (a type of life support). Researchers will measure changes in thigh muscle size and strength in 50 adults. The goal is to see if adding NMES to standard care helps patients maintain muscle while in the ICU.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients of both sexes aged 20 to 50 years * Patients receiving extracorporeal membrane oxygenation (ECMO) (veno-venous or veno- arterial) * Patients admitted to the ECMO unit for at least 72 hours * Hemodynamically stable patients as determined by the treating medical team * Patients medically eligible for participation in physiotherapy and neuromuscular electrical stimulation (NMES) Exclusion Criteria: * Hemodynamic instability * Patients requiring ECMO support for less than 72 hours * Unstable cardiac arrhythmias * Hemorrhagic shock * Deep venous thrombosis or pulmonary embolism * Lower limb open wounds or acute skin burns at electrode placement sites * Pregnant patients * Patients receiving intra-aortic balloon pump (IABP) support * Any contraindication to NMES application

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscle mass loss

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Faculty of physical therapy

    Cairo, Giza, Dokki, 11432, Egypt

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