New drug shows promise for nerve disease that affects walking
NCT ID NCT06482437
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Trial info
This study tested a new medicine called NMD670 in 81 adults with Charcot-Marie-Tooth disease types 1 and 2. Participants took either the drug or a placebo twice daily for 21 days. The main goal was to see if the drug could improve walking distance in 6 minutes. The study also checked safety and other measures of nerve function.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Aarhus University Hospital
Aarhus, Denmark
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Bicêtre University Hospital
Paris, 94275, France
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CHR de la Citadelle- Site Citadelle Neurolgie Boulevard du 12eme de Ligne 1
Liège, 4000, Belgium
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CHU Marseille, Reference centre for neuromuscular diseases and ALS Department of Neuromuscular Diseases
Marseille, 13005, France
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Centre Hospitalier Universitaire De Nice
Nice, 06001, France
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Columbia University Medical Center
New York, New York, 10032, United States
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Hospital Universitari Vall d'Hebron
Barcelona, 8035, Spain
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Hospital Universitari i Politecnic La Fe de Valencia
Valencia, 46026, Spain
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Institut de Myologie Groupe Hospitalier Pitié-Salpêtrière
Paris, 75651, France
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Laboratoire d'Explorations Fonctionnelles, CHU Nantes
Nantes, France
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Mass General Neurology
Boston, Massachusetts, 02114, United States
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National Neuromuscular research Institute, PLLC
Austin, Texas, 78759, United States
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NextGen Precision Health
Columbia, Missouri, 65211, United States
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OSU Department of Neurology Division of Neuromuscular Diseases
Columbus, Ohio, 43221, United States
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Providence Medical Research Center
Spokane, Washington, 99204, United States
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Rigshospitalet, Department of Neurology
Copenhagen, Denmark
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University Hospitals Leuven, Department of Neurology
Leuven, 3000, Belgium
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University of Kansas Medical Center, Department of Neurology
Kansas City, Kansas, 66160, United States
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University of Rochester Neuromuscular Disease Center
Rochester, New York, 14642, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple blood test track nerve damage? a study investigates NT-3 levels in neuropathy.
- Could a simple device ease nerve pain in Charcot-Marie-Tooth?
- Gene study aims to decode rare nerve disorder variations
- CMT tremor mystery: new study aims to uncover hidden symptoms
- Scientists hunt for early warning signs of inherited nerve disease
- Wearable tech tracks fatigue in muscle disease patients