Immune cell boost shows promise for Tough-to-Treat leukemia

NCT ID NCT03068819

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 31 times

Summary

This study tested a new treatment for children and adults whose acute myeloid leukemia (AML) came back after a stem cell transplant. The treatment used specially trained immune cells (CIML NK cells) from the original donor, combined with standard donor lymphocyte infusions, to help the body fight the cancer. The goal was to see if this approach was safe and could lead to remission. The trial included 62 participants and focused on feasibility, safety, and leukemia-free survival.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.