Immune cell shot aims to tame tough lupus cases

NCT ID NCT06676631

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests whether adding NK cells (a type of immune cell) to the standard drug rituximab can safely help people with severe lupus or lupus-related kidney disease. The study will enroll 18 adults in China and focus on safety and signs of disease improvement. It is too early to know if this combination will be effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NK cells (NK010 or NK042) plus rituximab

What this could lead to

If it works, this could point toward a new treatment option for people with hard-to-control lupus or lupus kidney disease.

What could go wrong

This is a very early, small phase 1 trial with only 18 people. It primarily tests safety, not whether it works. Side effects from the NK cells or rituximab are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lupus nephritis systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guangdong Provincial People's Hospital

    RECRUITING

    Guangzhou, Guangdomg, 510080, China

    Contact Email: •••••@•••••