Immunotherapy before surgery shows promise against lung cancer

NCT ID NCT02259621

Ongoing Disease control Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

First seen Dec 18, 2025 · Last updated Jun 12, 2026 · Updated 29 times

Summary

This study tested giving immunotherapy drugs (nivolumab alone or with ipilimumab) before surgery to people with a type of lung cancer called non-small cell lung cancer. The goal was to see if this approach is safe and helps shrink tumors before removal. 39 participants were enrolled, and researchers measured side effects and how much of the tumor remained after treatment.

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Contacts and locations

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Locations

Johnathan Spicer

Montreal, Quebec, H4 3J1, Canada
Johns Hopkins at Bayview Medical Center

Baltimore, Maryland, 21224, United States
Memorial Sloan Kettering

New York, New York, 10065, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Baltimore, Maryland, 21287, United States
Swedish Cancer Insitute

Edmonds, Washington, 98026, United States

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER NON-SMALL CELL LUNG CANCER