Immunotherapy drug nivolumab takes on rare blood cancer in kids and adults

NCT ID NCT03703050

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests the immunotherapy drug nivolumab in 45 children and adults with a rare blood cancer called ALK-positive anaplastic large cell lymphoma that has come back or not responded to treatment. Participants are split into two groups: those with active disease to see if the drug shrinks tumors, and those already in remission after relapse to see if it keeps the cancer away. The goal is to find a new treatment option for this hard-to-treat cancer.

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Conditions

The condition(s) this trial relates to.

ALK-positive anaplastic large cell lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Bordeaux

    Bordeaux, France

  • CHU Bordeaux Hopital Pellegrin

    Bordeaux, 33076, France

  • CHU Mondor

    Créteil, France

  • CHU Toulouse Hopital des enfants

    Toulouse, 31059, France

  • CHU de nancy

    Vandœuvre-lès-Nancy, 54500, France

  • Centre Léon Berard Lyon

    Lyon, 69008, France

  • Centre Oscar Lambret

    Lille, France

  • Gustave Roussy

    Villejuif, Val de Marne, 94805, France

  • Hôpital Saint Louis

    Paris, 75010, France

  • Hôpital Trousseau

    Paris, Paris, 75012, France

  • IUC Toulouse

    Toulouse, 31059, France

  • Rigshospitalet

    Copenhagen, Denmark

  • Women'S and Children'S Nhs Foundation Trust

    Birmingham, United Kingdom