New combo tackles resistant cancers in small trial

NCT ID NCT03607890

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tests whether combining two immunotherapy drugs, nivolumab and relatlimab, can shrink or control advanced solid tumors with a specific genetic feature (MSI-H) that have stopped responding to prior PD-(L)1 therapy. About 38 adults with these hard-to-treat cancers will receive the drug combination. The main goal is to see how many patients' tumors shrink, while also monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Sidney Kimmel Comprehensive Cancer Center

    Baltimore, Maryland, 21231, United States

Conditions

Explore the condition pages connected to this study.