New study checks safety of combining two blood vessel drugs

NCT ID NCT07431294

Not yet recruiting Knowledge-focused Sponsor: Bayer Source: ClinicalTrials.gov ↗

First seen Mar 01, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This early-stage study looks at whether it is safe to take nitroglycerin spray together with a new drug called nurandociguat in people with stable coronary artery disease. Both drugs widen blood vessels, so combining them might cause a sudden drop in blood pressure. The study will monitor side effects and how the drugs interact in the body. About 36 adults aged 40 to 80 with stable CAD will take part.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Comac Medical | Phase I Clinical Research Unit

    Sofia, Sofia City Province, 1000, Bulgaria

  • Deutsches Herzzentrum der Charité (DHZC) - Klinik für Kardiologie, Angiologie und Intensivmedizin CVK

    Berlin, 13353, Germany

  • SocraTec R&D Erfurt-Clinical Pharmacology Unit

    Erfurt, 99084, Germany

  • UK Bonn Institut für Klinische Chemie und Klinische Pharmakologie, Phase I Einheit und Arzneimitteltherapiesicherheit

    Bonn, 53127, Germany

  • Universitätsklinikum Heidelberg - Zentrum für Innere Medizin, Abteilung Klinische Pharmakologie und Pharmakoepidemologie

    Heidelberg, 69120, Germany

Conditions

Explore the condition pages connected to this study.