Doctors test whether common breathing treatment actually helps newborns with rare defect

NCT ID NCT05213676

Summary

This study aims to find out if stopping the routine use of inhaled nitric oxide (a gas treatment to help with breathing) during the initial stabilization of newborns with a congenital diaphragmatic hernia affects their survival or need for advanced life support. It will involve about 600 babies born with this condition across multiple hospitals. Researchers will compare outcomes when hospitals use their standard protocol versus when they stop using this specific gas treatment early on.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Emory University & Children's Healthcare of Atlanta (CHOA)

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Email: •••••@•••••

  • Harvard University & Boston Children's Hospital (Harvard-BCH)

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

  • Indiana University & Riley Children's Hospital (IU-RiCH)

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Email: •••••@•••••

  • Medical University of South Carolina Children's Health (MUSC)

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Email: •••••@•••••

  • Randall Children's Hospital-Portland (RCH)

    RECRUITING

    Portland, Oregon, 97227, United States

    Contact Email: •••••@•••••

  • Stanford University & Lucile Packard Children's Hospital (Stanford-LPCH)

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Email: •••••@•••••

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alabama & Children's Hospital of Alabama (UAB-CoA)

    RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact Email: •••••@•••••

  • University of Arkansas & Arkansas Children's Hospital (UA-ACH)

    RECRUITING

    Little Rock, Arkansas, 72202, United States

    Contact Email: •••••@•••••

  • University of California, San Diego & Rady Children's Hospital (UCSD-Rady)

    RECRUITING

    San Diego, California, 92123, United States

    Contact Email: •••••@•••••

  • University of California-Irvine & Children's Hospital of Orange County (UC-CHOC)

    RECRUITING

    Irvine, California, 92868, United States

    Contact Email: •••••@•••••

  • University of Colorado & Children's Hospital of Colorado (CU-CHC)

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Email: •••••@•••••

  • University of Louisville & Norton Children's Hospital (UL-NCH)

    RECRUITING

    Louisville, Kentucky, 40202, United States

    Contact Email: •••••@•••••

  • University of Michigan & CS Mott Children's Hospital (UM-CSMott)

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Email: •••••@•••••

  • University of Southern California & Children's Hospital Los Angeles (USC-CHLA)

    RECRUITING

    Los Angeles, California, 90027, United States

    Contact Email: •••••@•••••

  • University of Tennessee & LeBonheur Children's Hospital (UT-LBCH)

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Email: •••••@•••••

  • University of Utah & Primary Children's Hospital (Utah-PCH)

    RECRUITING

    Salt Lake City, Utah, 84108, United States

    Contact Email: •••••@•••••

  • University of Washington & Seattle Children's Hospital (UW-SCH)

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Email: •••••@•••••

  • Vanderbilt University & Vanderbilt University Medical Center (VUMC)

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.