New drug tested for rare tumors in young women
NCT ID NCT07176689
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times
Summary
This study tests the drug nirogacestat in 50 premenopausal women (ages 18-40) with desmoid tumors, a rare type of non-cancerous growth. The main goal is to see how the drug affects ovarian function and to monitor any side effects. Participants will take the drug and be followed for changes in menstrual cycles and hormone levels.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cambridge University Hospitals NHS Foundation Trust
RECRUITINGCambridge, CB2 0QQ, United Kingdom
Contact Email: •••••@•••••
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Cliniques Universitaires Saint-Luc (CUSL)
RECRUITINGBrussels, 1200, Belgium
Contact Email: •••••@•••••
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Fondazione Policlinico Unversitario Campus Bio-Medico di Roma
RECRUITINGRoma, 00128, Italy
Contact Email: •••••@•••••
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Fondazione del Piemonte per l'Oncologia Istituto di Candiolo IRCCS
RECRUITINGCandiolo, Torino, 10060, Italy
Contact Email: •••••@•••••
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Hospital General Universitario Gregorio Maranon
RECRUITINGMadrid, 28007, Spain
Contact Email: •••••@•••••
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Hospital General Universitario Gregorio Maranon
RECRUITINGMadrid, 28041, Spain
Contact Email: •••••@•••••
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Hospital Universitario Jimenez Diaz
RECRUITINGMadrid, 28040, Spain
Contact Email: •••••@•••••
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Hospital Universitario La Paz
RECRUITINGMadrid, 28046, Spain
Contact Email: •••••@•••••
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Hospital Universitario Miguel Servet
RECRUITINGZaragoza, 50009, Spain
Contact Email: •••••@•••••
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Hospital Universitario y Politecnico La Fe
RECRUITINGValencia, 46026, Spain
Contact Email: •••••@•••••
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Hospital de la Santa Creu i Sant Pau
RECRUITINGBarcelona, 08041, Spain
Contact Email: •••••@•••••
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IRCCS Azienda Ospedaliero-Universitaria S. Orsola
RECRUITINGBologna, 40138, Italy
Contact Email: •••••@•••••
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IRCCS Istituto Ortopedico Rizzoli
RECRUITINGBologna, 40136, Italy
Contact Email: •••••@•••••
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Istituto Nazionale Tumori I.R.C.C.S- Fondazione G. Pascale
RECRUITINGNaples, 80131, Italy
Contact Email: •••••@•••••
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Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" IRCCS IRST. S.r.l.
RECRUITINGMeldola, Forli-Cesena, 47104, Italy
Contact Email: •••••@•••••
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LUMC
RECRUITINGLeiden, 2333 ZA, Netherlands
Contact Email: •••••@•••••
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Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis (NKI-AVL)
RECRUITINGAmsterdam, 1066 CX, Netherlands
Contact Email: •••••@•••••
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The Christie NHS Foundation Trust
RECRUITINGManchester, M20 4BX, United Kingdom
Contact Email: •••••@•••••
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The Royal Marsden NHS Foundation Trust
RECRUITINGLondon, SW3 6JJ, United Kingdom
Contact Email: •••••@•••••
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University College London Hospitals NHS Foundation Trust
RECRUITINGLondon, NW1 2PG, United Kingdom
Contact Email: •••••@•••••
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Universitätsklinikum Mannheim, Mannheim Cancer Center
RECRUITINGMannheim, 68167, Germany
Contact Email: •••••@•••••
Conditions
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