Ovarian cancer drug trial halted: niraparib vs chemo showdown ends early

NCT ID NCT06964165

First seen Dec 26, 2025 · Last updated May 16, 2026 · Updated 19 times

Summary

This study aimed to see if the drug niraparib works better than standard chemotherapy before surgery for people with advanced (stage III/IV) ovarian cancer that has a specific genetic feature called HRd. The trial was stopped early after enrolling 36 participants. Researchers measured how many tumors shrank or disappeared with each treatment.

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Contacts and locations

Locations

  • GSK Investigational Site

    San Francisco, California, 94115, United States

  • GSK Investigational Site

    Miami, Florida, 33136, United States

  • GSK Investigational Site

    Tampa, Florida, 33606, United States

  • GSK Investigational Site

    Scarborough, Maine, 04074, United States

  • GSK Investigational Site

    Boston, Massachusetts, 02114, United States

  • GSK Investigational Site

    St Louis, Missouri, 63141, United States

  • GSK Investigational Site

    New York, New York, 10029, United States

  • GSK Investigational Site

    New York, New York, 77030, United States

  • GSK Investigational Site

    Rochester, New York, 14642, United States

  • GSK Investigational Site

    Sioux Falls, South Dakota, 57105, United States

  • GSK Investigational Site

    Seattle, Washington, 98104, United States

  • GSK Investigational Site

    Ottawa, Ontario, K1H 8L6, Canada

  • GSK Investigational Site

    Montreal, Quebec, H2X 0A9, Canada

  • GSK Investigational Site

    Montreal, Quebec, H4A 3J1, Canada

  • GSK Investigational Site

    A Coruña, ES, 15006, Spain

  • GSK Investigational Site

    Madrid, ES, 28027, Spain

  • GSK Investigational Site

    Madrid, ES, 28033, Spain

  • GSK Investigational Site

    Madrid, ES, 28050, Spain

  • GSK Investigational Site

    Madrid, ES, 28223, Spain

  • GSK Investigational Site

    Málaga, ES, 29001, Spain

  • GSK Investigational Site

    Pamplona, ES, 31008, Spain

Conditions

Explore the condition pages connected to this study.