Can a second-line drug help CML patients stay cancer-free without daily pills?

NCT ID NCT01774630

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 31 adults with chronic myeloid leukemia (CML) whose cancer came back after they stopped taking imatinib. They were given nilotinib, a more powerful targeted therapy, to see if it could make their cancer undetectable again and allow them to stop treatment once more. The goal was to measure how many patients remained relapse-free three years after starting nilotinib.

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Conditions

The condition(s) this trial relates to.

chronic myelogenous leukemia, BCR-ABL1 positive Leukemia, Myelogenous, Chronic, BCR-ABL Positive Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH Valence

    Valence, 26953, France

  • CH d'Annecy

    Pringy, 74374, France

  • CHU Angers

    Angers, 49033, France

  • CHU de Nice, Service Hématologie Clinique

    Nice, 06202, France

  • CHU de Toulouse, Service d'Hématologie

    Toulouse, 31059, France

  • Centre Hospitalier Lyon Sud, Service Hématologie

    Pierre-Bénite, 69495, France

  • Centre Hospitalier de Versailles - Hôpital André Mignot - Service de Médecine B

    Le Chesnay, 78157, France

  • Hôpital Haut Lévêque, Service Hématologie

    Pessac, 33604, France

  • Hôpital Pontchaillou

    Rennes, 35033, France

  • Institut Bergonié

    Bordeaux, 33076, France

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