New drug may offer better nighttime heartburn relief than current standard

NCT ID NCT07268820

First seen Jan 05, 2026 · Last updated May 08, 2026 · Updated 26 times

Summary

This study compares two medications, zastaprazan and esomeprazole, to see which one better relieves nighttime heartburn in people with erosive reflux disease (GERD). About 160 Korean adults with nighttime heartburn will take one of the two drugs for several weeks. The goal is to find which treatment helps them sleep without heartburn-related disturbances, improving their quality of life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Catholic University of Korea, Incheon ST. Mary's Hospital

    RECRUITING

    Incheon, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chonnam National University Hospital

    RECRUITING

    Gwangju, South Korea

  • Gangnam Severance Hospital

    RECRUITING

    Seoul, South Korea

  • Hallym University Chuncheon Sacred Heart Hospital

    RECRUITING

    Chuncheon, South Korea

  • Korea University Ansan Hospital

    RECRUITING

    Ansan, South Korea

  • Kyung Hee University Hospital

    RECRUITING

    Seoul, South Korea

  • Kyungpook National University Chilgok Hospital

    RECRUITING

    Chilgok, South Korea

  • Pusan National University Hospital

    RECRUITING

    Busan, South Korea

  • Pusan National University Yangsan Hospital

    RECRUITING

    Yangsan, South Korea

  • Soonchunhyang University Hospital

    RECRUITING

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.