Nighttime blood sugar spikes linked to fatty liver in type 1 diabetes?
NCT ID NCT05933018
First seen Sep 25, 2026 ยท Last updated Sep 25, 2026
Summary
Researchers want to know whether high blood sugar at night and early morning relates to fatty liver in people with type 1 diabetes. The study includes 100 adults with type 1 diabetes who use an insulin pump and a continuous glucose monitor. Participants are split into two groups based on whether they have nighttime high blood sugar. Everyone receives a liver scan to check for fat and stiffness, and researchers compare the groups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, it could help doctors identify who with type 1 diabetes faces fatty liver risk and guide earlier monitoring.
- What could go wrong
- This observational study cannot prove cause and effect, and the findings may not apply to people who do not use insulin pumps or glucose sensors.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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100 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Jul 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * type 1 diabetes patients * C- PEPTIDE level \<0.6 * continuous glucose monitoring system * insulin pump users Exclusion Criteria: * pregnancy * type 2 diabetes * non-pump or sensor users * unwilling to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Emek Medical Center
Afula, Israel/Zaphon, 1834160, Israel
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