Could nicotine patches slow memory loss? scientists test surprising treatment

NCT ID NCT02720445

Completed Disease control Sponsor: University of Southern California Source: ClinicalTrials.gov ↗

Summary

This study tested whether wearing a nicotine skin patch daily for two years could improve memory, thinking, and daily function in older adults with mild cognitive impairment. Researchers enrolled 348 participants aged 55-90 who were experiencing early memory problems but not full dementia. Half received nicotine patches (increasing to 21mg/day) and half received placebo patches, with neither participants nor researchers knowing who got which.

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Contacts and locations

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Locations

Augusta University Movement and Memory Disorders

Augusta, Georgia, 30912, United States
Brain Matters Research

Delray Beach, Florida, 33445, United States
Brain Matters Research

Stuart, Florida, 34997, United States
Central Arkansas Veterans Healthcare System

North Little Rock, Arkansas, 72205, United States
Central States Research (formerly Tulsa Clinical Research)

Tulsa, Oklahoma, 74104, United States
Georgetown University

Washington D.C., District of Columbia, 200072145, United States
Glenn Biggs Institute at the University of Texas Health

San Antonio, Texas, 78229, United States
Headlands Eastern MA LLC

Plymouth, Massachusetts, 02360, United States
Houston Methodist Neurological Institute

Houston, Texas, 77030, United States
Integrative Clinical Trials

New York, New York, 11229, United States
JEM Research Institute

Atlantis, Florida, 33462, United States
Kingfisher Cooperative, LLC

Spokane, Washington, 99202, United States
LeHigh Valley Hospital

Allentown, Pennsylvania, 18105, United States
Miami Jewish Health Systems

Miami, Florida, 33137, United States
Mount Sinai School of Medicine

New York, New York, 100296552, United States
Neurology Clinic, P.C.

Cordova, Tennessee, 38018, United States
New York University Medical Center

New York, New York, 100166055, United States
Northwestern University

Chicago, Illinois, 606113010, United States
Nuvance Health Medical Practice Ct, Inc.; Associated Neurologists, PC

Danbury, Connecticut, 06810, United States
Ohio State University

Columbus, Ohio, 43210, United States
Penn State Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Perseverance Research Center

Scottsdale, Arizona, 85254, United States
Providence Brain and Spine Institute

Portland, Oregon, 97225, United States
Ralph H. Johnson VA Health Care System

Charleston, South Carolina, 294011113, United States
SUNY Upstate Medical University

Syracuse, New York, 13210, United States
Sharp Neurocognitive Research Center

San Diego, California, 92123, United States
Syrentis Clinical Research

Santa Ana, California, 92705, United States
USC Rancho Los Amigos

Downey, California, 90242, United States
University at Buffalo (UBMD)

Buffalo, New York, 14203, United States
University of Iowa

Iowa City, Iowa, 52242, United States
University of Washington Memory and Brain Wellness Center

Seattle, Washington, 98195, United States
University of Wisconsin

Madison, Wisconsin, 53706, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37212, United States
Velocity Clinical Research - Boise

Meridian, Idaho, 83642, United States
Velocity Clinical Research - Syracuse

East Syracuse, New York, 13057, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.

MILD COGNITIVE IMPAIRMENT